Why pharmacy matters in pregnancy
Most pregnant women take at least one over the counter medication during pregnancy, and a significant percentage take a prescription medication for an existing condition. Whether you have a chronic condition you have managed for years or you are dealing with a new symptom (heartburn, headache, congestion, nausea), the question of what is safe is unavoidable.
Your OB-GYN is the right clinician for your pregnancy. Your pharmacist is the right clinician for your medications. The two roles are complementary.
What is generally considered safe for common pregnancy complaints
This is general guidance, not personal advice. Anything specific to your situation should be confirmed with your OB-GYN or a pharmacist.
Headache and minor pain
Acetaminophen (Tylenol) at the lowest effective dose and shortest duration is the standard recommendation. Ibuprofen, naproxen, and aspirin are generally avoided in pregnancy, particularly in the third trimester.
Heartburn and reflux
Calcium based antacids (Tums) are considered safe and often the first choice. Famotidine (Pepcid) is widely considered safe in pregnancy when stronger relief is needed.
Nausea
Vitamin B6 (pyridoxine) is the first line. Doxylamine plus pyridoxine, available OTC or as the combination prescription Diclegis, is widely used and well studied in pregnancy. Stronger antiemetics are available by prescription when needed.
Congestion and cold symptoms
Saline nasal sprays are safe and effective. Decongestant pills containing pseudoephedrine are usually avoided in the first trimester and discussed individually after. Most antihistamines have a long pregnancy safety record.
Allergies
Loratadine and cetirizine have been studied extensively and are widely considered safe. Diphenhydramine has a long safety record but causes more sedation.
Prescription medications you may already be taking
Many chronic condition medications need adjustment when you become pregnant. Some need to continue at the same dose. Some need to be switched. Some need to be stopped. Categories that frequently require review:
- Blood pressure medications. ACE inhibitors and ARBs are not appropriate in pregnancy. Methyldopa, labetalol, and nifedipine are commonly used alternatives.
- Antidepressants. Many SSRIs have been studied extensively in pregnancy. The decision to continue, switch, or stop is highly individual and should be a conversation with both your psychiatrist or prescriber and your OB-GYN.
- Diabetes medications. Insulin remains the standard for diabetes management in pregnancy. Metformin is used in specific situations.
- Thyroid medications. Levothyroxine continues, and the dose typically needs to be increased during pregnancy. Antithyroid medications may need to be switched.
- Anti seizure medications. Decisions about continuing or switching require a neurologist and a pharmacist.
- Acne medications. Isotretinoin and several topical medications must be stopped before conception.
Supplements and prenatal vitamins
Prenatal vitamins are essential, ideally started before conception. Folic acid at least 400 mcg daily, ideally more for women with specific risk factors. Iron, calcium, vitamin D, and DHA are all common in prenatal formulations. Not all prenatals are equal, and a pharmacist can help you pick one that fits your situation, particularly if you have nausea (which can make many prenatals worse) or specific deficiencies.
Beyond the prenatal, many supplements are not well studied in pregnancy and should be discussed before continuing. Herbal supplements in particular vary widely in safety profile, and many commonly used ones are not recommended in pregnancy.
Where Fairview fits in your pregnancy team
We are not your OB-GYN. We do not replace your physician. What we are is the clinician most easily reached, with the most current pharmacology information, and the most time per conversation. Serving Hattiesburg, the Pine Belt, Central Mississippi, and South Mississippi.
Many of our Mississippi pregnant patients use us as a first call for any medication question. Is this safe. Is the dose appropriate. Are these two things okay together. The answer is free, the answer is fast, and it gets escalated to your OB-GYN if your situation warrants a clinician higher up the chain.
When to call a pharmacist immediately
- You are pregnant or planning pregnancy and currently take a prescription medication.
- You bought an OTC medication and want to confirm it is appropriate for your trimester.
- You are using a supplement and are not sure whether it is appropriate in pregnancy.
- You missed a dose of a chronic condition medication during pregnancy.
- You have severe morning sickness and the standard recommendations have not been enough.
- You are breastfeeding and want to know if a medication is appropriate.
This article is for general information only and is not a substitute for personalized medical advice. Before starting or changing any medication, including over the counter products and supplements, talk with your pharmacist or physician about your specific situation.
References
- CDCMedicine and PregnancyPublic health resource
- FDAPregnancy and MedicinesConsumer information
