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Medication Safety

What Is a Prescription Drug Monitoring Program, And Why Does My Pharmacist Check It?

The state database your pharmacist checks before filling a controlled substance, what it shows, and why it protects you.

What Is the PDMP?

A Prescription Drug Monitoring Program, PDMP, is a state operated electronic database that tracks the dispensing of controlled substances. Every time a pharmacy fills a prescription for a Schedule II, III, or IV controlled substance, that transaction is reported to the state PDMP database.

The information recorded typically includes: the patient’s name, date of birth, and address; the prescriber’s name and DEA number; the medication name, dose, and quantity dispensed; the date filled; and the dispensing pharmacy’s information.

Every state in the United States now operates a PDMP. Most states require pharmacists and prescribers to check the PDMP before dispensing or prescribing certain controlled substances. Mississippi’s PDMP, the Mississippi Prescription Monitoring Program, operates under the Mississippi State Board of Pharmacy.

What Does Your Pharmacist Actually See?

When your pharmacist pulls up your PDMP record, they can see your controlled substance prescription history across all pharmacies in the state, and in many cases across multiple states, as interstate data sharing has expanded significantly in recent years.

They can see: every controlled substance prescription filled for you in the reporting period, which prescribers wrote those prescriptions, which pharmacies dispensed them, the dates of each fill, and the quantities.

They cannot see your non controlled prescriptions, your medical records, your diagnosis, or your insurance information through the PDMP. It is specifically a controlled substance dispensing history, nothing more.

Why Does This Database Exist?

The PDMP was created in response to a documented public health crisis: the widespread diversion and misuse of prescription opioids and other controlled substances that accelerated through the 1990s and 2000s.

Before PDMPs existed, a patient could visit multiple physicians in the same week, receive overlapping opioid prescriptions from each one, and fill all of them at different pharmacies with no single provider or pharmacist aware of the full picture. This practice, commonly called prescription shopping or doctor shopping, contributed directly to addiction, overdose, and the diversion of prescription medications into illegal markets.

The PDMP created visibility where there had been none. It did not eliminate the problem, but it gave prescribers and pharmacists a clinical tool to identify patterns that warranted a conversation, or a refusal to dispense.

What Happens If the PDMP Shows a Concerning Pattern?

If a pharmacist reviews a patient’s PDMP record and sees patterns that raise clinical concerns, multiple prescribers, overlapping prescriptions, fills at many different pharmacies, quantities that exceed standard clinical parameters, they have both the authority and the professional responsibility to address it.

That might mean asking the patient questions about their other prescribers. It might mean contacting the prescriber to verify the clinical rationale. It might mean declining to dispense the prescription and documenting the reason.

It is important to understand that a pharmacist declining to fill a controlled substance is not always, or even usually, an accusation. It is sometimes a clinical judgment that the prescription as presented raises safety concerns that need to be resolved before dispensing is appropriate.

Does the PDMP Treat All Patients the Same?

It should, and in a well run pharmacy it does. The PDMP is a clinical tool, not a profiling tool. A patient with chronic pain who has been on a stable opioid regimen with the same prescriber for three years will show a very different PDMP pattern than a patient who has seen six prescribers in ninety days. Those patterns are clinically meaningful, and that is exactly what the tool is designed to help pharmacists and prescribers identify.

If you have ever felt that a pharmacist’s PDMP check felt judgmental or discriminatory rather than clinical, that is a legitimate concern worth raising, with the pharmacy directly, with your state board of pharmacy, or with a pharmacist you trust enough to have an honest conversation.

What This Means for You as a Patient

The PDMP check is not something to be afraid of if you are receiving controlled substances appropriately from a treating physician for a legitimate medical condition. It is a safety net, one that exists to protect you as much as anyone else.

The best thing you can do as a patient is maintain a transparent relationship with one prescriber and one pharmacy. When your complete picture is visible to a pharmacist who knows you, the PDMP becomes confirmation of appropriate care rather than a source of concern.

This article is for general information only and is not a substitute for personalized medical advice. Before starting or changing any medication, including over the counter products and supplements, talk with your pharmacist or physician about your specific situation.

References

  1. CDCPrescription Drug Monitoring ProgramsPublic health overview
  2. Mississippi Board of PharmacyMississippi Prescription Monitoring ProgramState program

Medically reviewed by Mike Acheampong, PharmD

Last reviewed May 20, 2026

This article is for educational purposes and does not replace personalized advice from a licensed healthcare professional. Always read product labels and consult your pharmacist or physician before starting, stopping, or combining medicines.

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