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Fairview Pharmacy
Patient medication guide

Biktarvy, made simple.

Biktarvy is a once a day pill that treats HIV. It is a complete regimen, which means it is the whole treatment in one tablet. This guide explains how it works, how to take it, what to watch for, and how to get help with the cost. A Mississippi pharmacist who fills Biktarvy wrote it for you, with care.

This guide is here to teach you. It is not medical advice, and it does not replace your doctor or pharmacist. Always do what your doctor tells you, and ask a pharmacist before you change how you take any medicine.

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What Biktarvy is and why your doctor gave it to you

Biktarvy is a once a day pill for HIV. It holds three medicines in one small tablet.

It is a complete regimen. That is an important phrase. It means Biktarvy by itself is the whole HIV treatment. You do not add other HIV pills to it. If you are ever unsure whether a pill is your whole treatment or just one part, ask your pharmacist. We will check it against what your doctor intended.

Biktarvy keeps the amount of HIV in your blood very low, so low that a test cannot find it. That is called being undetectable.

Here is the part worth holding onto. When HIV is kept undetectable by taking your medicine every day, it is not passed to others through sex. Doctors call this U equals U, undetectable equals untransmittable. Treatment protects your health, and it protects the people you care about.

How Biktarvy works

To make more of itself, HIV has to get inside your cells and copy itself. It uses a few different steps to do that.

The three medicines in Biktarvy block those steps. One blocks the virus from inserting itself into your cells. The other two block the virus from copying itself.

When those steps are blocked, the virus cannot multiply. The amount of HIV in your blood drops, usually until a test can no longer find it, and your immune system gets the chance to stay strong. This works only while you keep taking the pill every day.

Your dose

Biktarvy is one tablet, once a day. You can take it with or without food. Take it at about the same time every day.

Your doctor picks your dose and your pharmacist checks it. This page will not tell you what dose to take. The most important thing with Biktarvy is not the size of the dose, it is taking it every single day, on schedule. That steady, daily habit is what keeps the virus controlled.

Timing, and what to do if you miss a dose

Take Biktarvy once a day, at about the same time each day. Many people tie it to something they already do daily, like brushing their teeth or a morning coffee, so it is easy to remember.

HIV medicine works best when it is taken every day without gaps. Missed doses give the virus a chance to copy itself and, over time, to become harder to treat. So the goal is simple: do not miss doses.

If you miss a dose:

  • If you miss a dose, take it as soon as you remember on the same day.
  • If it is already the next day, skip the missed dose and take your normal dose. Do not take two in one day.
  • Never take two doses at once to catch up.
  • If missing doses is happening often, tell us. We can help with reminders, refill timing, and packaging that makes it easier.

Side effects, what is normal and what is not

Common, and usually mild.

  • Loose stools or some stomach upset.
  • Nausea.
  • A headache.
  • These are most common early on and often settle as your body adjusts.

Call your doctor if you see:

  • Unusual muscle pain, weakness, or tenderness.
  • Yellowing of your skin or the white of your eyes.
  • Stomach pain with nausea or vomiting that does not settle.
  • New or worsening low mood, sadness, or anxiety. This is worth a call, not something to wait out.

Go to the emergency room right away if:

  • You have a severe rash, or skin that is blistering or peeling.
  • You have fast breathing, severe weakness, muscle pain, and a cold feeling in your hands and feet. These can be signs of a rare but serious problem.
  • You have signs of liver trouble: severe nausea and vomiting, pain on the upper right side of your belly, and yellow skin or eyes.

What to be careful with

A few medicines do not mix with Biktarvy, and a couple of common ones just need careful timing. None of this is hard once you know it.

There are two medicines that must never be taken with Biktarvy: a heart rhythm medicine called dofetilide, and a tuberculosis medicine called rifampin. The herbal supplement St. John's Wort and some seizure medicines are also not a good match. This is not a list to memorize. It is a reason to do one simple thing.

Common antacids, the kind with aluminum or magnesium, can block Biktarvy from being absorbed if taken at the same time. You can still use them. Just take Biktarvy at least 2 hours before, or at least 6 hours after, the antacid. Calcium and iron supplements are fine taken together with Biktarvy if you take them with food.

The simple rule: before you start or stop any medicine, a prescription, an over the counter pill, or a supplement, tell your pharmacist you take Biktarvy. Every single time. At Fairview, we check every new prescription against your full list.

What it costs

The cost is different for every person, because every insurance plan is different.

Here is the honest way to find your price. If you pay cash, call Fairview and we will give you a price for your situation. If you have private insurance, there may be a coupon or a savings program from the maker of the drug that helps lower your cost, and we will check if one is available for you. The best step is to let a pharmacist look at your plan. We do this for every patient.

Do not let cost make you skip doses. Call us first. There is almost always something we can do.

There is also a generic version of many medicines. The generic is the same medicine. Ask your pharmacist if a generic is a good fit for you.

What should be checked

Before you start Biktarvy, and while you take it, your care team checks a few things to keep you safe and to confirm the medicine is working.

Your doctor should check:

  • Your HIV viral load, the amount of virus in your blood, to confirm it stays undetectable.
  • Whether you have hepatitis B, which should be tested before you start.
  • How well your kidneys and your liver are working.
  • A lab value called creatinine. Biktarvy can nudge this number up a little, and that early bump is expected. It does not mean your kidneys are being harmed.

Your pharmacist should:

  • Check every new medicine and supplement against Biktarvy.
  • Make sure you have your refills on time, with no gaps.
  • Answer questions about side effects, timing, and cost.
  • Keep your information private, always.

At Fairview, we keep an eye on our Biktarvy patients. If a refill is running late, we call you, because a gap in HIV medicine matters. Your prescription is handled discreetly and with respect, every time.

Special situations

If you also have hepatitis B.

You should be tested for hepatitis B before you start Biktarvy. This matters because if you have both HIV and hepatitis B, stopping Biktarvy later, without a plan, can cause a serious flare of the hepatitis B. It is not a reason to avoid Biktarvy. It is a reason to never stop it on your own, and to make sure your doctor knows your hepatitis B status.

Never stop on your own.

If you ever want to stop Biktarvy, or switch, talk to your doctor first and make a plan together. Stopping suddenly lets the virus rebound, and for people with hepatitis B it can cause a dangerous liver flare. There is almost always a safe way to make a change. It just needs to be planned.

Pregnancy.

If you are pregnant, planning to become pregnant, or breastfeeding, tell your HIV doctor. HIV treatment in pregnancy is important and is planned carefully. There is a pregnancy registry that helps track HIV medicines in pregnancy. Your doctor will choose what is right for you and your baby.

Travel.

Keep Biktarvy in your carry on bag, never a checked bag. Bring extra in case of delays. If you cross time zones, ask your pharmacist how to keep your once a day timing steady. A small medicine list with Fairview's number is handy to carry.

Cost should never be the reason you stop.

HIV medicine is expensive, but there is a lot of help, and most people end up paying very little. There are manufacturer programs, and for people with limited income there are assistance programs that can provide the medicine at low or no cost. If cost is a worry, call Fairview before you ever skip a dose. We will help you find the right program.

How Fairview helps Biktarvy patients

When you fill Biktarvy at Fairview, here is what you get. This is normal care for us, and it is always private.

At your first fill:

  • We check all your medicines and supplements against Biktarvy.
  • We explain the timing rules for antacids and supplements.
  • We help you set up an easy daily routine so doses are not missed.
  • We talk through cost and help you find any program you qualify for.

At every refill:

  • We check your file for any new medicines.
  • We make sure there is no gap before your next refill.
  • We answer any new questions, privately.

On our own, without being asked:

  • If a refill is running late, we call you.
  • If we see a medicine that does not mix with Biktarvy, we call your doctor.
  • We check your cost at every fill to keep it as low as possible.
  • We keep your care discreet and respectful, always.

Questions people ask about Biktarvy

Yes. Biktarvy is a complete regimen. It holds three medicines in one pill, and it is the whole treatment. You do not add other HIV pills to it. If you are ever unsure, ask your pharmacist to confirm.

Related guides

Have a question about your Biktarvy? Ask a pharmacist you can trust.

Living well with HIV comes down to one steady habit: taking your medicine every day. Fairview is here to make that easy, private, and affordable. If something made you wonder, ask us. And if you want a pharmacy that handles your care with discretion and respect, moving your prescription to us takes one phone call.

Medical disclaimer. This guide is here to teach you. It is not medical advice, and it does not replace your doctor or pharmacist. Always do what your doctor tells you, and ask a pharmacist before you change how you take any medicine. Information about Biktarvy can change. This page was last reviewed on the date shown.

Written by Dr. Mike Acheampong, PharmD, MPH, a licensed Mississippi pharmacist.

Last reviewed: [Month Year].

Sources: FDA prescribing information for Biktarvy, revised February 2024; manufacturer information.

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